CardioWise Announces Research Milestones with MRI Analysis Software

Fayetteville medical software company CardioWise on Friday announced developmental milestones resulting from a year-long federal grant award period in which it moved closer to commercialization of a non-invasive method for detection of heart disease.

In 2013, CardioWise received Phase I and IB Small Business Innovation and Research grants from the National Science Foundation to further develop its patent-pending MRI analysis software -- Multiparametric Strain (or MPS) heart analysis -- that can analyze the three-dimensional motion of the heart acquired from cardiac MRI images and produce a four-dimensional model. 

CardioWise is a portfolio company of VIC Technology Venture Development of Fayetteville and a client firm of Innovate Arkansas and the Arkansas Science & Technology Authority.

The milestones announced on Friday are:

  • Development of cloud-based software that enables health-care providers and patients to download CardioWise analysis to any browser-based device in accordance with federal guidelines including HIPAA.
  • Automation and testing of MRI analysis software, currently done by hand, that reduces total analysis time from six hours to less than 30 minutes and enables an entire image acquisition and analysis to be completed in a single office visit.
  • Clinical validation of the software on separate MRI scans acquired on the same patient on the same MRI, as well as scans acquired on the same patient but on different MRI systems.  

The CardioWise analysis detects portions of the heart that are moving abnormally and demonstrates to what degree the heart muscle has been affected, said CardioWise CEO Jack Coats.

"Since MRI uses no ionizing radiation or contrast, it is completely non-invasive and poses no risk to the patient," he said. "This diagnostic analysis method may aid doctors to determine what intervention, such as surgery, stent insertion, or drug is most appropriate for the patient who presents with cardiovascular disease symptoms."